Cherubs work undercover posing as normal children and therefore rarely use weapons such as knives or guns. However, they frequently go on missions where the people they investigate are armed and dangerous. All CHERUB agents are trained to disarm people and are taught how to use and disable the most common types of firearms.

Where a cherub is put in a situation where they are at high risk of being assaulted, they are occasionally issued with a non-lethal weapon, such as a can of pepper spray or an electric stun gun (Taser). Agents are only allowed to use them in a critical situation where their life is in danger. The use of such a weapon is likely to be regarded as highly suspicious behaviour for a child and the undercover mission will be terminated immediately.